Archive | Sleeping Pills

Influential Report Advises Against Sleeping Pill Use By The Elderly

The Beers list uses specific criteria to identify and list inappropriate, high risk drugs in the elderly that should be avoided in favor of a non-drug approach or safer medications because the high risk of toxicity and adverse side effects clearly outweigh the benefits. The Beers list was originally developed in 1991 and subsequently expanded…

Sleep Medications Are Not Clinically Effective In A Large Number Of Patients

A new study on the real-world effectiveness of sleeping pills found they do not alleviate insomnia in most cases. The study assessed the effects of benzodiazepine-type sleep medications (including Ambien, Lunesta, Dalmane, Restoril, and Sonata) on insomnia remission rates in a clinical sample of almost 200 patients with real-world comorbidities such as pain, anxiety, or…

FDA Petitioned to Revise Warnings About Sleeping Pills and Add “Black Box” warning

A Citizens Petition was submitted to the Food and Drug Administration to revise warnings about hypnotics (sleeping pills), including possible black box warning for evidence of a serious hazard associated with their use. The petition, which is summarized below,  was submitted by Dr. Daniel Kripke, professor emeritus at the University of California at San Diego…

Sleeping Pills are Only Marginally Effective

There is little evidence that the newer generation sleeping pills such as Ambien or Lunesta are more effective than older sleeping pills such as Dalmane or Restoril. There is, however, plenty of research to suggest that they are only mildly effective just like their predecessors. A meta analysis of sleeping pill studies published in 2006…

Sleeping Pills and Reward Pathways

Drug dependency implies tolerance, in which increasing doses of the drug are required to produce an effect, or withdrawal symptoms such as anxiety, agitation, or physical stress reactions when the individual attempts to stop using the drug. Drug addiction involves drug use that adversely affects occupational, personal, or social functioning because the individual cannot stop…